2009 Fiscal Year Final Research Report
Immunological and genetic analysis of disease resistant native livestock
| Project/Area Number |
20780214
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Hokkaido University |
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Principal Investigator |
KONNAL Satoru Hokkaido University, 大学院・獣医学研究科, 准教授 (40396304)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 在来種家畜 / 抗病性 / 疾患感受性 / 遺伝子多型 / サイトカイン / IFN-γ / 原虫感染症 / ウイルス感染症 |
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| Research Abstract |
To attempt to identify immunological and genetic factors promoting the disease susceptibility in native livestock, cytokine profiles were analyzed, and then determined whether there are any polymorphisms in the cytokine genes. We found that the expression levels of TNF-a and IFN-y and transcription activities of the promoter/predicted enhancer region of the genes were higher in individuals with disease resistant than in susceptible individuals. These data suggest that the findings could at least in part contribute to the disease resistance in native livestock.
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[Journal Article] Development and application of a quantitative real-time PCR for the diagnosis of Surra in water buffaloes.2009
Author(s)
Konnai S, Mekata H, Mingala C.N., Abes N.S., Gutierrez C.A., Herrera R.V., Dargantes A.P., Witola W.H., Cruz L.C., Inoue N., Onuma M., Ohashi K.
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Journal Title
Infect. Genet. Evol. 9
Pages: 449-452
Peer Reviewed
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[Journal Article] A survey of abortifacient infectious agents in livestock in Luzon, the Philippines, with emphasis on the situation in a cattle herd with abortion problems.2008
Author(s)
Konnai S, Mingala C. N, Sato M, Abes N. S, Venturina F.A., Gutierrez C.A., Sano T, Omata Y, Cruz L.C., Onuma M, Ohashi K.
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Journal Title
Acta Trop. 105
Pages: 269-273
Peer Reviewed
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[Journal Article] Serological survey of Toxoplasma god!! in wild waterfowl in Chukotka, Kamchatka, Russia and Hokkaido, Japan.2008
Author(s)
Murao T, Omata Y, Kano R, Murata S, Okada T, Konnai S, Asakawa M, Ohashi K, Onuma M.
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Journal Title
J. Parasitol. 94
Pages: 830-803
Peer Reviewed
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[Journal Article] Prevalence and Source of Typanosome Infections in Field-Captured Vector Flies (Glossina pallidipes) in Southeastern Zambia.2008
Author(s)
Mekata H, Kornai S, Simmunza M, Chembensof M, Kano R, Witra W. H, Tembo M. E, Chitanbo H, Inoue N, Onuma M, Ohashi K.
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Journal Title
J. Vet. Med. Sci. 70
Pages: 923-928
Peer Reviewed
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[Journal Article] Effects of anti-tick cocktail vaccine against Rhipicephalus appendiculatus.2008
Author(s)
Imamura S, Konnai S, Vaz I da S, Yamada S, Nakajima C, Ito Y, Tajima T, Yasuda J, Simuunza M, Onuma M, Ohashi K
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Journal Title
Jpn J Vet Res. 56
Pages: 85-98
Peer Reviewed
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