2009 Fiscal Year Final Research Report
Molecular and cellular biological studies on diversity of inclusion bodies and pathogenesis of Chlamydophila psittaci.
| Project/Area Number |
20780218
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied veterinary science
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| Research Institution | Gifu University |
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Principal Investigator |
OHYA Kenji Gifu University, 応用生物科学部, 准教授 (50402219)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 人獣共通感染症 |
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| Research Abstract |
cell cytoplasm, called "inclusion body". In this study, aiming at understanding the relationship between biogenesis of inclusion bodies of Chlamydophila psittaci, a causative agent for a zoonotic psittacosis, and its pathogenesis. As a result of C. psittaci library screening by using C. psittaci-infection specific serum, the clone encoding one of the polymorphic membrane protein (pmp) genes was obtained (temporary named as PmpX), and functional analysis of PmpX was done. Currently, further investigation of the role of C. psittaci Pmp family proteins (especially PmpX) in biogenesis of chlamydial inclusion bodies and in pathogenesis are on going.
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Research Products
(9 results)
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[Journal Article] Chlamydophila felis CF0218 is a novel TMH-family protein with potential as a diagnostic antigen for diagnosis of C. felis infection.2008
Author(s)
Ohya, K., Takahara, Y., Kuroda, E., Koyasu, S., Hagiwara, S., Sakamoto, M., Hisaka, M., Morizane, K., Ishiguro, S., Yamaguchi, T., Fukushi H.
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Journal Title
Clin. Vaccine Immunol 15(10)
Pages: 1606-1615
Peer Reviewed
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