2010 Fiscal Year Final Research Report
The nucleolar histone deacetylases involved in leaf development
| Project/Area Number |
20780239
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Applied molecular and cellular biology
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| Research Institution | Nagoya University |
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Principal Investigator |
UENO Yoshihisa Nagoya University, 理学研究科, 助教 (20335011)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 発生 / 分化制御 |
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| Research Abstract |
The AS2/LOB-domain protein, ASYMMETRIC LEAVES2 (AS2), and nucleolar localized histone deacetylases, HDT1/2, are involved in the determination of leaf shape in Arabidopsis. However, the molecular mechanisms underlying these phenomena are largely unknown. I investigated the functions of missense mutants of AS2 and HDT1/2 proteins. The missense mutants of AS2 revealed that the in vivo function of AS2 required the formation of hetero-tetramer including the N-termini of AS1 through the AS2/LOB-domain. The AS1-AS2 complex localizes the speckled bodies adjacent nucleoli, in which HDT1/2 localize. The analyses of HDT1/2 provide the further understanding of the mechanism underlying the synergistic interaction between the AS1-AS2 complex and HDT1/2.
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[Journal Article] Arabidopsis AUXIN RESPONSE FACTOR6 and 8 Regulate Jasmonic Acid Biosynthesis and Floral Organ Development via Repression of Class 1 KNOX Genes.2010
Author(s)
Tabata, R., Ikezaki, M., Fujibe, T., Aida, M., Tian, C.E., Ueno, Y., Yamamoto, K.T., Machida, Y., Nakamura, K., Ishiguro, S.
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Journal Title
Plant Cell Physiol. 51(1)
Pages: 164-175
Peer Reviewed
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[Journal Article] Genetic networks regulated by ASYMMETRIC LEAVES1 (AS1) and AS2 in leaf development in Arabidopsis thaliana : KNOX genes control five morphological events.2010
Author(s)
Ikezaki, M., Kojima, M., Sakakibara, H., Kojima, S., Ueno, Y., Machida, C., Machida Y.
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Journal Title
Plant J. 61(1)
Pages: 70-82
Peer Reviewed
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