• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2009 Fiscal Year Final Research Report

Synthetic Studies of Natural Products Containing an Eight-Membered Ring Featuring Tandem Carbon-Carbon Bond Formation.

Research Project

  • PDF
Project/Area Number 20790011
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Chemical pharmacy
Research InstitutionHiroshima University

Principal Investigator

SASAKI Michiko  Hiroshima University, 医歯薬学総合研究科, 助教 (30379888)

Project Period (FY) 2008 – 2009
Keywords合成化学
Research Abstract

A Brook rearrangement-mediated [3+4] annulation was applied to the synthesis of some natural products containing eight-membered ring system. We have accomplished the synthesis of the core of asteriscanolide and the formal syntheses of (+)-laurallene and (+)-prelaureatin.

  • Research Products

    (6 results)

All 2009 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results) Remarks (2 results)

  • [Journal Article] Stereoselective Brook Rearrangement-Mediated SE2' Protonation of a-Hydroxy Allyl Silanes2009

    • Author(s)
      Michiko Sasaki, Yuri Shirakawa, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda
    • Journal Title

      Chem. Eur. J 15

      Pages: 3363-3366

    • Peer Reviewed
  • [Journal Article] Diastereoselective Brook Rearrangement-Mediated [3 + 4] Annulation: Application to a Formal Synthesis of (+)-Laurallene2008

    • Author(s)
      Michiko Sasaki, Azusa Hashimoto, Koudai Tanaka, Masatoshi Kawahata, Kentaro Yamaguchi, Kei Takeda
    • Journal Title

      Org. Lett 10

      Pages: 1803-1806

    • Peer Reviewed
  • [Presentation] Use of a Brook Rearrangement- Mediated [3 + 4] Annulation Toward the Total Synthesis of (+)-Prelaureatin2009

    • Author(s)
      Michiko Sasaki, Kazuhisa Oyamada, Kei Takeda
    • Organizer
      41st National Organic Chemistry Symposium
    • Place of Presentation
      Boulder, CO, USA
    • Year and Date
      2009-06-08
  • [Presentation] Trapping of Chiral Carbanions by [2, 3]-Wittig Rearrangement2008

    • Author(s)
      Michiko Sasaki, Hidaka Ikemoto, Mariko Higashi, Kei Takeda
    • Organizer
      The 236th National Meeting of the American Chemical Society (Sci-Mix)
    • Place of Presentation
      Philadelphia, PA, USA
    • Year and Date
      2008-08-18
  • [Remarks]

    • URL

      http://home.hiroshima-u.ac.jp/takedake/

  • [Remarks]

    • URL

      http://home.hiroshima-u.ac.jp/takedake/index-e.html

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi