2009 Fiscal Year Final Research Report
Functional and molecular analysis of DSCR1 as a regulator of vascular morphology
Project/Area Number |
20790168
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
General anatomy (including Histology/Embryology)
|
Research Institution | Nippon Medical School |
Principal Investigator |
FUJIWARA Masakazu Nippon Medical School, 老人病研究所, 助教 (20312069)
|
Project Period (FY) |
2008 – 2009
|
Keywords | 発生学 / 形態形成学 |
Research Abstract |
Morphology of blood vessels is diverse. However, we do not know how these morphological variations are made during vasculogenesis/angiogenesis. In this study, we found that DSCR1 regulates the morphology of blood vessels by suppressing the branching of blood vessels during vasculogenesis/angiogenesis. In the near future, we may generate blood vessels with appropriate morphology for the patients by using DSCR1 as a new vasculogenesis/angiogenesis suppressor.
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Research Products
(5 results)