2009 Fiscal Year Final Research Report
Novel mechanisms of t-PA-dependent liver regeneration
| Project/Area Number |
20790182
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
General physiology
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| Research Institution | Kinki University |
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Principal Investigator |
KAWAO Naoyuki Kinki University, 医学部, 助教 (70388510)
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| Project Period (FY) |
2008 – 2009
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| Keywords | t-PA / 細胞内シグナル伝達 / 肝再生 |
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| Research Abstract |
The roles of plasminogen activator (PA) /plasmin system in liver repair was examined. Then, the PA/plasmin system contributes to hepatocyte proliferation. In addition, plasminogen is essential for triggering a cascade of sequential repair responses after liver injury.
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