2011 Fiscal Year Final Research Report
Global analysis for miRNA of cancer stemcells in follicular lymphoma
| Project/Area Number |
20790288
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Human pathology
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| Research Institution | Iwate Medical University |
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Principal Investigator |
ABO Akiko (八嶋 亜紀子) 岩手医科大学, 医学部, 講師 (80326686)
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| Project Period (FY) |
2008 – 2011
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| Keywords | 濾胞性リンパ腫 / がん幹細胞 / microRNA / SP細胞 |
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| Research Abstract |
We investigated the differential expression of miRNAs between SP cells and non-SP cells of human follicular lymphomas(FLs). This study demonstrates that down expression of microRNA contribute to the down regulation of multipotent stem cell transcription factor in SP cells, and that over expression of microRNA targeting BCL6.
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[Journal Article]2008
Author(s)
Mitomo S, Maesawa C, Ogasawara S, Iwaya T, Shibazaki M, YashimaAbo A, Kotani K, Oikawa H, Sakurai E, Izutsu N, Kato K, Komatsu H, Ikeda K, Wakabayashi G, Masuda T
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Journal Title
Cancer Sci
Volume: 99
Pages: 280-6
Peer Reviewed
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