2009 Fiscal Year Final Research Report
Functional analysis of novel protein secretion system, T6SS in Vibrio parahaemolyticus
Project/Area Number |
20790335
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Bacteriology (including Mycology)
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Research Institution | Osaka University |
Principal Investigator |
AKEDA Yukihro Osaka University, 微生物病研究所, 特任講師 (60444527)
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Project Period (FY) |
2008 – 2009
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Keywords | 腸炎ビブリオ / タンパク質分泌機構 |
Research Abstract |
There are various protein secretion systems in pathogenic gram-negative bacteria. Recently, a novel protein secretion system, T6SS, has been reported. In this project, it has been found that V. parahaemolyticus has a T6SS. which can secrete and translocate a novel protein in T6SS-dependent manner. This protein secretion requires N-terminal region of a novel secreted protein.
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[Journal Article] Two regulators of Vibrio parahaemolyticus play important roles in enterotoxicity by controlling the expression of genes in the Vp-PAI region2010
Author(s)
Toshio Kodama, Kazuyoshi Gotoh, Hirotaka Hiyoshi, Mikiharu Morita, Kaori Izutsu, Yukihiro Akeda, Kwon-Sam Park, Vlademir Cantarelli, Rikard Dryselius, Tetsuya Iida, Takeshi Honda
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Journal Title
Peer Reviewed
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