2009 Fiscal Year Final Research Report

Exercise tolerance and left ventricular diastolic function during exercise in patients with diastolic heart failure

Research Project

Project/Area Number	20790524
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Circulatory organs internal medicine
Research Institution	Mie University
Principal Investigator	MASAKI Tanabe Mie University, 医学部・附属病院, 助教 (50456737)
Project Period (FY)	2008 – 2009
Keywords	心エコー / スペックルトラッキング法 / 運動負荷 / 臥位エルゴメーター / 拡張期心不全 / 左室拡張能
Research Abstract	Cardiac performance during exercise was evaluated using novel echocardiographic techniques in normal subjects. All datasets from parasternal views were obtained. Speckle tracking imaging datasets from apical views were analyzed in 8 of 10 subjects. During exercise, cardiac output and E/e' increased with exercise stress. On the other hand, stroke volume and global systolic strain did not change with exercise. Cardiac performance during exercise can be evaluated, and has potential for clinical applications.