2010 Fiscal Year Final Research Report
Investigation into modifying factors in patients with hypertrophic cardiomyopathy caused by an identical disease-causing mutation
| Project/Area Number |
20790533
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Circulatory organs internal medicine
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| Research Institution | Kochi University |
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Principal Investigator |
KUBO Toru Kochi University, 教育研究部医療学系, 助教 (80325422)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 臨床心血管病態学 |
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| Research Abstract |
I investigated the genotype-phenotype correlations in hypertrophic cardiomyopathy (HCM). In genetic analysis, I reported some mutations associated with HCM, particularly mutations in cardiac myosin-binding protein C gene. In the studies of clinical phenotype in HCM, I focused on the left ventricular remodeling of this disease and reported several results including the usefulness of biomarkers for predicting the prognosis.
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