2010 Fiscal Year Final Research Report

Pathological study and transplantation of Bone marrow stromal cell in a model of amyotrophic lateral sclerosis

Research Project

Project/Area Number	20790614
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Neurology
Research Institution	Tottori University
Principal Investigator	KITAYAMA Michio Tottori University, 医学部, 助教 (70379650)
Project Period (FY)	2008 – 2010
Keywords	モデルマウス
Research Abstract	Histological examination of the transgenic mice tissue at ventral horn using General stain and immunohistochemisity. Although the result is a nerve cell shedding onset after severe would mutant SOD1 are each in nerve cells, aging degenerative in organelle and inclusion bodies in cells had emerged from early. Therapeutic effect of Bone marrow stromal cell transplantation for anterior mice in quality between cell bone marrow, after consideration of clinical and pathological tissue chemically. However, as a result, port group in the life-prolonging effects, and histologically also remained a spinal cord ventral horn cells, but as a clinical effect was not enough.

(5 results)