2009 Fiscal Year Final Research Report
Development of the quantitative method and the analysis of function of the molecular marker for acute graft-versus-host disease.
| Project/Area Number |
20790735
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
YAMAMOTO Masaki Sapporo Medical University, 医学部, 助教 (80404664)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 血液学 / 造血幹細胞移植 / 移植片対宿主病 / バイオマーカー / ケモカイン |
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| Research Abstract |
We studied about chemokine CCL8 as a biomarker of acute graft-versus-host disease (GVHD). We developed ELISA for plasma CCL8 level in the GVHD mouse models. We analyzed the expression mechanism of CCL8 using in vitro and in vivo model.
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