2009 Fiscal Year Final Research Report
Diagnostic usefulness of salivary steroid hormone measurement by LC-MS/MS in girls with PCOS
| Project/Area Number |
20790745
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Pediatrics
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| Research Institution | Keio University |
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Principal Investigator |
AMANO Naoko Keio University, 医学部, 助教 (70348689)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 小児内分泌学 / 肥満 / 思春期 / ステロイドホルモン |
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| Research Abstract |
I measured salivary free steroid hormones by liquid chromatography-tandem mass spectrometry (LC-MS/MS), and compared the steroid hormone levels of obesity girls to non-obesity girls. The levels of DHEA, androstenedione and testosterone in obesity girls were significantly higher than those in non-obesity girls. I think that the secretions of those androgens are increased in obesity girls as well as adult women with polycystic ovary syndrome.
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