2009 Fiscal Year Final Research Report
Analysis of PDA pathogenesis with novel PDA model mice.
| Project/Area Number |
20790775
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Chubu University |
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Principal Investigator |
YAJIMA Ichiro Chubu University, 生命健康科学研究所, 研究員 (80469022)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 色素細胞学 / 循環器学 / 発生学 / 腫瘍学 |
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| Research Abstract |
Tyr : : Cre ; ss-catFloxedEx3 mice were generated by crossing Tyr : : Cre transgenic mice with ss-catFloxedEx3 mice. These mice showed PDA by enhanced activity of ss-catenin after birth. In these mice, ectopic melanocytes were localized in the heart and they directly and/or indirectly affect formation of the PDA.
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