2009 Fiscal Year Final Research Report
A basic study of next generate varicella zoster virus vaccine
| Project/Area Number |
20790820
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Dermatology
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| Research Institution | Jikei University School of Medicine |
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Principal Investigator |
ITO Hideki Jikei University School of Medicine, 医学部, 講師 (70360138)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 水痘 / 帯状疱疹 / 水痘帯状疱疹ワクチン / 次世代ワクチン |
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| Research Abstract |
ORF39 gene of VZV is essential for replication of VZV. We tried to insert a unique AvrII site which is located between ORF65 and ORF66, however, no virus is replicated. We guess the location of VZV gene ORF39 is important for replication of VVZ.
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