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2009 Fiscal Year Final Research Report

Chronotherapy to mood disorders and It's mechanism

Research Project

  • PDF
Project/Area Number 20790828
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionAkita University

Principal Investigator

ECHIZENYA Masaru  Akita University, 医学部, 講師 (60420056)

Project Period (FY) 2008 – 2009
Keywords精神生理学
Research Abstract

Sleep deprivation induces a rapid amelioration of mood in about 60% of depressed patients. After the next night of sleep, however, most patients experience a relapse. Previous studies demonstrated that some interventions could prevent a relapse. In this study, we tried total sleep deprivation followed by sleep phase advance and bright light therapy to drug-resistant depression. Treatment effects were evaluated by HAM-D (17 items and 6 items), SDS, VAS and SF-36. Twelve depressive patients (Unipolar/Bipolar=9/3) were treated in this protocol. According to the results, significant improvements were observed in HAM-D (17 items and 6 items), SDS, VAS and SF-36. Combined treatments in this study can be expected as clinically beneficial because drug-resistant patients improved in several days.

  • Research Products

    (5 results)

All 2009 Other

All Journal Article (1 results) Presentation (3 results) Remarks (1 results)

  • [Journal Article] Paradoxical reactions to hypnotic agents in adolescents with free-running disorder.2009

    • Author(s)
      Echizenya M, Iwaki S, Suda H, Shimizu T.
    • Journal Title

      Psychiatry Clin Neurosci. 63

      Pages: 428

  • [Presentation] (シンポジウム)うつ病に対する断眠療法2009

    • Author(s)
      越前屋勝
    • Organizer
      日本睡眠学会第34回定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      20091000
  • [Presentation] 深部体温リズムの前進に伴い睡眠覚醒リズムが改善した概日リズム睡眠障害、睡眠相後退型の3症例2009

    • Author(s)
      越前屋勝, 佐藤浩徳, 細川敬輔, 草薙宏明, 須田秀可, 寺門靖太郎, 清水徹男
    • Organizer
      日本睡眠学会第34回定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      20091000
  • [Presentation] 看護師の深夜勤務前の仮眠が深夜勤務中の自覚的眠気及び作業能率に及ぼす影響2009

    • Author(s)
      越前屋勝, 葛西菜摘, 岡根初美, 神原篤司, 清水徹男
    • Organizer
      日本睡眠学会第34回定期学術集会
    • Place of Presentation
      大阪
    • Year and Date
      20091000
  • [Remarks]

    • URL

      http://www.med.akita-u.ac.jp/~seisin/sleep_deprivation/web-content/index.html

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Published: 2011-06-18   Modified: 2016-04-21  

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