2010 Fiscal Year Final Research Report
Brain imaging study of cognitive disorder mechanism and cognitive behavioral therapy in depression
| Project/Area Number |
20790843
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Psychiatric science
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| Research Institution | Hiroshima University |
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Principal Investigator |
ONODA Keiichi Hiroshima University, 医学部, 助教 (60432712)
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| Project Period (FY) |
2008 – 2010
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| Keywords | うつ病 / fMRI / 認知行動療法 |
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| Research Abstract |
It is well known that depressive patients tend to think negatively. Beck suggested a cognitive theory of depression, which the nature was cognitive impairments. In the current study using functional magnetic resonance imaging (fMRI) under emotional tasks, we have investigated the neurophysiological basis of the cognition, relationship between the cognitive impairment of depression and brain function, and objective/quantitative evaluation of cognitive behavioral therapy effects.
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[Journal Article] Rostral anterior cingulate cortex activity mediates the relationship between the depressive symptoms and the medial prefrontal cortex activity.2010
Author(s)
Yoshimura, S., Okamoto, Y., Onoda, K., Matsunaga, M., Ueda, K., Suzuki, S., et al.
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Journal Title
J Affect Disord 122
Pages: 76-85
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[Journal Article] Decreased ventral anterior cingulate cortex activity is associated with reduced social pain during emotional support.2009
Author(s)
Onoda, K., Okamoto, Y., Nakashima, K., Nittono, H., Ura, M., Yamawaki, S.
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Journal Title
Soc Neurosci 4
Pages: 443-454
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[Journal Article] Self-referential processing of negative stimuli within the ventral anterior cingulate gyrus and right amygdala.2009
Author(s)
Yoshimura, S., Ueda, K., Suzuki, S., Onoda, K., Okamoto, Y., Yamawaki, S.
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Journal Title
Brain Cogn 69
Pages: 218-225
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[Journal Article] Anterior cingulate cortex modulates preparatory activation during certain anticipation of negative picture.2008
Author(s)
Onoda, K., Okamoto, Y., Toki, S., Ueda, K., Shishida, K., Kinoshita, A., et al.
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Journal Title
Neuropsychologia 46
Pages: 102-110
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[Journal Article] Does low self-esteem enhance social pain? The relationship between trait self-esteem and anterior cingulate cortex activation induced by ostracism.
Author(s)
Onoda, K., Okamoto, Y., Nakashima, K., Nittono, H., Yoshimura, S., Yamawaki, S., Yamaguchi, S., Ura, M.
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Journal Title
Soc Cogn Affect Neurosci. in press
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[Remarks] ホームページ等
