2009 Fiscal Year Final Research Report
Estimation of coronary endothelial dysfunction in metabolic syndrome and effects of treatment on the dysfunction
| Project/Area Number |
20790871
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Hokkaido University |
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Principal Investigator |
NAYA Masanao Hokkaido University, 大学院・医学研究科, 非常勤講師 (20455637)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 循環器 / PET / 心筋血流量 / メタボリックシンドローム |
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| Research Abstract |
Coronary vascular reactivity assessed by PET and cold pressor test was reduced and its severity was associated with serum LDL cholesterol and oxidative stress in patients with metabolic syndrome. Reduction of coronary flow reserve was associated coronary plaque extent in patients with more advanced coronary artery disease. These results suggest that coronary atherosclerosis is observed even in metabolic syndrome patients without symptoms of angina and progresses to the atherosclerotic plaque and reduction of coronary flow reserve.
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Research Products
(17 results)
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[Presentation] Myocardial oxidative metabolism in patients with aortic valve stenosis.2009
Author(s)
Naya M, Keiichiro Y, Sugiki T, Iwano H, Kuge Y, Yamada S, Katoh C, Matsui Y, Tsutsui H, Tamaki N.
Organizer
Society of Nuclear Medicine
Place of Presentation
Tronto, Canada
Year and Date
20090613-20090617
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[Presentation] Effects of smoking cessation on coronary endothelial dysfunction in young and middle-aged healthy smokers.2009
Author(s)
Naya M, Keiichiro Y, Sugiki T, Iwano H, Kuge Y, Yamada S, Katoh C, Matsui Y, Tsutsui H, Tamaki N
Organizer
The 73rd Annual Scientific Meeting of the Japanese Circulation Society
Place of Presentation
Osaka, Japan
Year and Date
20090320-20090322
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