2009 Fiscal Year Final Research Report

Study on quantitative evaluation of respiratory-induced organ motion and high-precision particle cancer therapy

Research Project

Project/Area Number	20790878
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Radiation science
Research Institution	Gunma University
Principal Investigator	TASHIRO Mutsumi Gunma University, 重粒子線医学推進機構, 助教 (60447274)
Project Period (FY)	2008 – 2009
Keywords	放射線治療 / 粒子線治療 / 呼吸性移動
Research Abstract	Lung motion evaluation techniques have been studied using CT images in order to make highly precise radiation/particle therapy for lung cancer with respiratory motion. The extraction methods of lung areas and vessels with realistic CT images, which would influence on the motion tracking accuracy, have been investigated, and the unnecessarily fine structure extraction of lung borders and vessels could be suppressed. Verification on respiratory gated-irradiation of heavy-ion therapy for lung tumors has been carried out to realize the high-precision therapy. Particularly, investigations have been carried out on evaluation of motion errors and margins, and how to deal with the margins in heavy-ion treatment planning system. The validity has been verified by beam tests with a motion phantom.