2009 Fiscal Year Final Research Report
Development of a novel method for reducing renal accumulation of radiolabeled peptides
| Project/Area Number |
20790882
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
AKIZAWA Hiromichi Health Sciences University of Hokkaido, 薬学部, 准教授 (90311795)
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| Project Period (FY) |
2008 – 2009
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| Keywords | がん / アイソトープ内用療法 / 体内動態制御 / 放射性医薬品 / 腎臓 / 刷子縁膜 / 酵素 / ペプチド |
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| Research Abstract |
When radiolabeled carcinophilic peptides are administered to cure cancer, renal accumulation of radioactivity, which causes side effect, is observed. My goal is the development of a novel strategy for reducing the renal radioactivity by the action of enzymes in kidneys. Useful information on the development was obtained from the present study.
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