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2009 Fiscal Year Final Research Report

Development of a novel method for reducing renal accumulation of radiolabeled peptides

Research Project

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Project/Area Number 20790882
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Radiation science
Research InstitutionHealth Sciences University of Hokkaido

Principal Investigator

AKIZAWA Hiromichi  Health Sciences University of Hokkaido, 薬学部, 准教授 (90311795)

Project Period (FY) 2008 – 2009
Keywordsがん / アイソトープ内用療法 / 体内動態制御 / 放射性医薬品 / 腎臓 / 刷子縁膜 / 酵素 / ペプチド
Research Abstract

When radiolabeled carcinophilic peptides are administered to cure cancer, renal accumulation of radioactivity, which causes side effect, is observed. My goal is the development of a novel strategy for reducing the renal radioactivity by the action of enzymes in kidneys. Useful information on the development was obtained from the present study.

  • Research Products

    (1 results)

All 2009

All Presentation (1 results)

  • [Presentation] 抗体のオクタアルギニン修飾が細胞への結合性に及ぼす影響2009

    • Author(s)
      宮本怜、秋澤宏行、上原知也、東佑翼、二木史朗、花岡宏史、飯田靖彦、遠藤啓吾、荒野泰
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-27

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Published: 2011-06-18   Modified: 2016-04-21  

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