2009 Fiscal Year Final Research Report
Evaluation of [C-11]benzyl acetate as a marker of glial metabolism
| Project/Area Number |
20790895
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Radiation science
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| Research Institution | Osaka University |
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Principal Investigator |
MOMOSAKI Sotaro Osaka University, 大学院・医学系研究科, 助教 (30379268)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ベンジルアセテート / グリア代謝 / 脳内動態 / PET / ラット |
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| Research Abstract |
As a marker of glial metabolism, [<11>^C]benzyl acetate ([<11>^C]BA) was synthesized and evaluated in living rat brain using positron emission tomography (PET). We succeed the synthesis of [<11>^C]BA, the measurement of distribution in the living rat brain and the kinetic analysis in this study. The results show that [<11>^C]BA is a good candidate for the measurement of glial metabolism.
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