A study of the axonal diameter based on the restricted water diffusion using MRI

2009 Fiscal Year Final Research Report

• Project/Area Number: 20790918
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Radiation science
• Research Institution: Central Institute for Experimental Animals
• Principal Investigator: HIKISHIMA Keigo Central Institute for Experimental Animals, 病理病態研究部, 研究員 (30420219)
• Project Period (FY): 2008 – 2009
• Keywords: 磁気共鳴画像(MRI)

Research Abstract

Diffusion magnetic resonance imaging (MRI) enables us to observe the restricted water mobility resulted from various microstructure in vivo. We developed an analysis of the axonal diameter using q-space diffusion MRI. This new method could be powerful tool for monitoring pathological conditions in clinical practice.

Research Products

• [Journal Article] 高分解能High b-value多軸拡散計測による視交叉神経走行追跡 (2009)
  • Author(s): 疋島啓吾、山田雅之、藤吉兼浩、百島祐貴、川井健司、中村雅也、玉置憲一、岡野栄之
  • Journal Title: 日本磁気共鳴医学会雑誌 29巻、1号 Pages: 41-44
  • Peer Reviewed
• [Presentation] q-spaceから見える組織構造 (2009)
  • Author(s): 疋島啓吾
  • Organizer: 第一回q-space研究会
  • Place of Presentation: 横浜
  • Year and Date: 2009-10-01
• [Presentation] q-space imagingを用いたmyelinの可視化 (2009)
  • Author(s): 疋島啓吾、藤吉兼浩、山田雅之、小牧裕司、百島祐貴、八木一夫、玉置憲一、戸山芳昭、中村雅也、岡野栄之
  • Organizer: 第37回日本磁気共鳴医学会大会
  • Place of Presentation: 横浜
  • Year and Date: 2009-10-01
• [Presentation] 高空間・高角度分解能拡散計測による視交叉神経走行の解析 (2008)
  • Author(s): 疋島啓吾、山田雅之、藤吉兼浩、百島祐貴、川井健司、中村雅也、玉置憲一、岡野栄之
  • Organizer: 第36回日本磁気共鳴医学会大会
  • Place of Presentation: 旭川
  • Year and Date: 2008-09-11
• [Presentation] q-space MRIのコモンマーモセット脊髄への適用 (2008)
  • Author(s): 疋島啓吾、中村雅也、藤吉兼浩、山田雅之、北村和也、百島祐貴、八木一夫、玉置憲一、戸山芳昭、岡野栄之
  • Organizer: 第31回日本神経科学大会
  • Place of Presentation: 東京
  • Year and Date: 2008-07-09
• [Presentation] In vivo high Resolution q-space imaging of the spinal cord injury in Nonhuman primates (2008)
  • Author(s): K. Hikishima, M. Nakamura, K. Fujiyoshi, M. Yamada, K. Kitamura, S. Momoshima, K. Yagi, N. Tamaoki, Y. Toyama, H. Okano
  • Organizer: 17th Annual Meeting of International Society of Magnetic Resonance in Medicine
  • Place of Presentation: Toronto, Canada
  • Year and Date: 2008-05-03