2009 Fiscal Year Final Research Report
Expression and localization of keratinocyte growth factor receptor (KGFR) in esophageal cancer and molecular target thrapy
| Project/Area Number |
20790975
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Digestive surgery
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| Research Institution | Nippon Medical School |
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Principal Investigator |
YOSHINO Masanori Nippon Medical School, 医学部, 助教 (10343609)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 食道外科学 |
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| Research Abstract |
The progress of the recent molecular target drug is remarkable, and the medicine associated with the growth factor receptor is applied clinically, and those effectiveness is confirmed. Therefore we thought that we could apply these treatment to even relatively developing esophageal cancer in the field of molecular target therapy and aimed at a role of keratinocyte growth factor receptor (KGFR) which played role that was important to proliferation of cells and angiogenesis in esophageal cancer. Progressed a study whether KGFR was associated with a proliferation of esophageal cancer whether we might prevent growth of esophageal cancer by inhibiting KGFR and examined it about the future as the molecular target therapy.
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