2009 Fiscal Year Final Research Report
Effects of omentopexy combined with granulocyte colony-stimulating factor in a rabbit heart model
| Project/Area Number |
20790985
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Thoracic surgery
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| Research Institution | Gifu University |
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Principal Investigator |
ISHIDA Narihiro Gifu University, 医学部附属病院, 医員 (90397331)
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| Project Period (FY) |
2008 – 2009
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| Keywords | G-CSF / 大網充填 / 血管新生 / 心機能 |
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| Research Abstract |
We investigated whether or not omentopexy combined with granulocyte colony-stimulating factor (G-CSF) subcutaneous administration reduced infarction area and improved left ventricular (LV) dysfunction in a coronary occlusion and reperfusion model. Echocardiography showed improvement of LV dysfunction and infarction/ischemic area ratio was reduced. Omentopexy with G-CSF administration improved LV function and decreased infarction area.
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