2009 Fiscal Year Final Research Report
Isolation and characterization of a novel peptide from gastrointenstinal tract associated with osteoblast differentiation and bone formation
| Project/Area Number |
20791058
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Orthopaedic surgery
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| Research Institution | Kurume University |
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Principal Investigator |
FUKUSHIMA Nobuhiro Kurume University, 医学部, 助教 (90412535)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ペプチド / 骨芽細胞 / 分化 / 骨密度 / 消化管 |
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| Research Abstract |
We discovered a novel peptide which is a positive regulator that acts directly on osteoblasts. This peptide directly promotes osteoblast differentiation in vitro and increases bone mineral density in vivo. The discovery of novel peptide may provide a new treatment option for osteoporosis and fracture healing.
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