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2009 Fiscal Year Final Research Report

The physiological function of RAMP whose expression is enhanced during embryogenesis and muscle regeneration.

Research Project

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Project/Area Number 20791059
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionKumamoto University

Principal Investigator

NAKAYAMA Yuki  Kumamoto University, 大学院・先導機構, 特定事業教員 (30332381)

Project Period (FY) 2008 – 2009
Keywords筋ジストロフィー / 筋再生 / マウス
Research Abstract

The aim of this study is to investigate the physiological function of RAMP whose expression is enhanced in skeletal muscles after injury. To elucidate the function of RAMP, I conducted a yeast two-hybrid screen to identify its interacting partners and isolated 7 clones. Furthermore, to elucidate the physiological function of RAMP in regenerating muscle, I started to produce the mice conditionally inactivated RAMP in skeletal muscle.

  • Research Products

    (5 results)

All 2009 2008 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (1 results) Remarks (1 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] CXCL14 and insulin action2009

    • Author(s)
      Hara T., Nakayama Y.
    • Journal Title

      Vitamins and Hormones 80

      Pages: 107-123

    • Peer Reviewed
  • [Journal Article] Promotion of spermatogonial proliferation by neuregulin 1 in newt (Cynops pyrrhogaster) testis2008

    • Author(s)
      Oral O., Uchida I., Eto K., Nakayama Y., Nishimura O., Hirao Y., Ueda J., Tarui H., Agata K. Abe S.
    • Journal Title

      Mech Dev 125(9-10)

      Pages: 906-917

    • Peer Reviewed
  • [Presentation] The expression and function of Brinp3 during skeletal muscle regeneration2009

    • Author(s)
      中山由紀、原孝彦
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-12-11
  • [Remarks]

    • URL

      http://sendou.kuma-u.jp/research/nakayama.html

  • [Patent(Industrial Property Rights)] 抗BRAK (CXCL14)ヒトモノクローナル抗体及びその用途2008

    • Inventor(s)
      原孝彦、寺沢(中山)由紀、波佐間正聡
    • Industrial Property Rights Holder
      東京都医学研究機構原孝彦、寺沢(中山)由紀
    • Industrial Property Number
      特許権PCT/JP2008/052603
    • Filing Date
      2008-12-02

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

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