2009 Fiscal Year Final Research Report
The role of the anterior cingulate cortex in the mechanisms underlying the neuropathic pain :
| Project/Area Number |
20791060
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Anesthesiology/Resuscitation studies
|
|---|
| Research Institution | Hokkaido University |
|---|
Principal Investigator |
TACHIBANA Kaori Hokkaido University, 北海道大学病院, 医員 (50374468)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | 疼痛管理学 |
|---|
| Research Abstract |
Neuropathic pain caused significant suppression of EPSPs in the ACC compared with rats subjected to sham surgery without altering the paired-pulse responses. These findings suggest that the alterations in EPSPs were not attributable to the presynaptic site of action. This abnormal excitability of the ATN-ACC synapse may be important in understanding the mechanism underlying neuropathic pain, particularly with respect to the affective and cognitive aspects.
|
