2009 Fiscal Year Final Research Report
Analysis of lipid microdomain under volatile anesthesia
| Project/Area Number |
20791078
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Kagawa University |
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Principal Investigator |
ONO Junichiro Kagawa University, 医学部附属病院, 助教 (90363217)
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| Research Collaborator |
SUZUKI Shingo 東京医科歯科大学, 難治疾患研究所, 特任講師 (50451430)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 麻酔学 / 揮発性麻酔薬 / 作用機序 / マイクロドメイン |
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| Research Abstract |
Microdomain in lipid bilayer may contribute to the mechanisms of volatile anesthesia. Isoflurane upregulated amount of cholesterol and protein contained in microdomain fraction extracted from mice brain. Total protein was particularly increased in isoflurane anesthesia.
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