2010 Fiscal Year Final Research Report
Pathosis and control of splanchnic circulation in septic shock
Project/Area Number |
20791080
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Anesthesiology/Resuscitation studies
|
Research Institution | Nagasaki University |
Principal Investigator |
SEKINO Motohiro Nagasaki University, 病院, 助教 (40380927)
|
Project Period (FY) |
2008 – 2010
|
Keywords | 敗血症性ショック / 腸管循環カ / ルペリチド |
Research Abstract |
In porcine fluid-resuscitated endotoxemia model, a low dose of carperitide, a synthetic atrial natriuretic peptide, administered prior to endotoxemia maintained systemic and splanchnic circulation, and prevented the deterioration of oxygenation. Carperitide infusion is a potentially beneficial therapy with respect to systemic and splanchnic circulation as well as the respiratory system during sepsis.
|
Research Products
(7 results)