2009 Fiscal Year Final Research Report
Clinical analysis of analgesic effect and mechanism of transdermal amitriptyline on refractory pain
| Project/Area Number |
20791081
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Anesthesiology/Resuscitation studies
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| Research Institution | Nagasaki University |
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Principal Investigator |
SAKAI Tetsuya Nagasaki University, 大学院・医歯薬学総合研究科, 助教 (70346948)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 抗うつ薬 / 経皮投与 / 難治性疼痛 / 電流知覚閾値 / 神経遮断効果 |
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| Research Abstract |
When amitriptyline is applied transdermally, quantitative and selective evaluation of sensory nerve shows that the blocking effect is exerted in all types of sensory fibers and lasts for four hours.
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