2009 Fiscal Year Final Research Report
Basic research for the anti cancer effect of Noscapine to Renal cell carcinoma and Prostate Cancer
| Project/Area Number |
20791103
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Urology
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| Research Institution | Kanazawa University |
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Principal Investigator |
MIYAGI Tohru Kanazawa University, 附属病院, 助教 (60467107)
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| Project Period (FY) |
2008 – 2009
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| Keywords | ノスカピン / 腎癌 / 前立腺癌 / 化学療法 |
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| Research Abstract |
We confirmed the anticancer effect of Noscapine to Renal cell carcinoma cell line and Prostate cancer cell line, they had been thought to be resistant to previous reported chemotherapy. Although IC50 to these cell lines need rather high concentration, still Noscapine was thought to be of great value as one of candidate for chemotherapy to renal cell carcinoma and prostate cancer patients, because there are several reports of safety of high dose Noscapine to human being.
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