2010 Fiscal Year Final Research Report
The basic study of the "reprogramming therapy of cancer using the cytosol of oocytes and ES cells.
| Project/Area Number |
20791140
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | University of Yamanashi |
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Principal Investigator |
FUKASAWA Hiroko University of Yamanashi, 大学院・医学工学総合研究部, 助教 (60362068)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 癌 / 体細胞核移植 / クローン胚 / ES細胞 / ntES細胞 |
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| Research Abstract |
Although the rate of development of cloned embryos to the blastocyst stage using the treated oocytes was lower than that obtained using fresh oocytes, three live pups were delivered after embryo transfer into pseudopregnant females (0.4% of the oocytes used). Thus, although cryopreservation reduces the potential of oocytes, these cells retain the ability to support the full-term development of cloned embryos.
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