2009 Fiscal Year Final Research Report
Regulation of placenta specific transcription factor GCMa/1 expression
| Project/Area Number |
20791172
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Obstetrics and gynecology
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| Research Institution | Kinjo Gakuin University |
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Principal Investigator |
YASUI Yuko Kinjo Gakuin University, 薬学部, 助教 (80434554)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 発現制御 / 胎盤 / GCMa / 1 / シグナル伝達 |
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| Research Abstract |
Glial cells missing a/1(GCMa/1)is a placenta specific transcription factor and essential for placental development and function. In this study, we investigated signal transduction mechanisms in regulation of GCMa/1 expression. We demonstrated that GCMa/1 expression is dependent upon PKC signaling pathway in addition to that of cAMP/PKA.
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