2009 Fiscal Year Final Research Report
The new method development of peptide immunotherapy
| Project/Area Number |
20791186
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | University of Yamanashi |
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Principal Investigator |
MATSUOKA Tomokazu University of Yamanashi, 大学院・医学工学総合研究部, 助教 (30313810)
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| Project Period (FY) |
2008 – 2009
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| Keywords | アレルギー / 免疫 / ペプチド |
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| Research Abstract |
We examined the T cells responses to antigen of Japanese cedar pollen in pollinosis patients. We compared antigen protein to 7 antigen peptides of Japanese cedar pollen. There are high responders and low responders for 7 antigen peptides in patients of Japanese cedar pollinosis. We stimulated lactic acid bacterium to dendritic cells and co-cultured with antigen protein of Japanese cedar pollen and T cells in patients of Japanese cedar pollinosis. Lactic acid bacterium have a effect of change T cells response for antigen protein of Japanese cedar pollen.
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