2010 Fiscal Year Final Research Report

Gene association study for the low tone hearing loss related diseases.

Research Project

Project/Area Number	20791188
Research Category	Grant-in-Aid for Young Scientists (B)
Allocation Type	Single-year Grants
Research Field	Otorhinolaryngology
Research Institution	Shinshu University
Principal Investigator	FUKUOKA Hisakuni Shinshu University, 医学部附属病院, 助教 (90419391)
Co-Investigator(Renkei-kenkyūsha)	USAMI Shinichi 信州大学, 医学部, 教授 (10184996) KITO Ryousuke 信州大学, 医学部, 助教 (80419358) NISHIO Shinya 信州大学, 医学部, 研究員 (70467166)
Project Period (FY)	2008 – 2010
Keywords	遺伝子 / 難聴 / 内耳 / 聴覚
Research Abstract	Some diseases including Meniere's disease and acute low tone sensory neural hearing loss indicate typical clinical feature, low tone hearing loss. WFS1 gene mutation which reported as a genetic cause of autosomal dominant type low tone sensory neural hearing loss. In this study, we perform gene association study of Meniere's disease. We determine 12 reported Menisre's disease associated SNPs and WFS1 gene SNP for 100 Meniere's disease patients, but we cannot found any statistical significant SNPs.

(2 results)