2009 Fiscal Year Final Research Report
Analysis of mucosal immunity inducement system associated CCL20/CCR6 in upper respiratory tract
| Project/Area Number |
20791204
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Otorhinolaryngology
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| Research Institution | Oita University |
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Principal Investigator |
ABE Nobuyuki Oita University, 医学部, 助教 (10433054)
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| Project Period (FY) |
2007 – 2009
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| Keywords | 鼻科学 |
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| Research Abstract |
BALB/c mice were immunized intranasally OVA and MIP-3α/CCL20. The dendritic cell was induced to NALT in the eminence for an immunohistochemistry . However, OVA specific immune response of IgG and IgA was not induced in the examination of ELISA. It was suggested not to have to the adjuvant effect in the passing nosal vaccine though MIP-3α/CCL20 was able to induce the dendritic cell from this to the immunity inducement tissue.
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