2009 Fiscal Year Final Research Report
Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization
| Project/Area Number |
20791271
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Ophthalmology
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| Research Institution | Keio University |
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Principal Investigator |
KOTO Takashi Keio University, 医学部, 助教 (60464814)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 脈絡膜血管新生 / 加齢黄斑変性 / CD44 |
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| Research Abstract |
Pathogene si s of chor oidal neov ascular izat ion involve s mac r ophage ac t ivati on. On the other hand, extr ac el lular matr ix, such as hyalur onan, r egulate s mac r ophage s ac cumulat ion. We r eveal ed that the hyalur onan - CD44 signal ing i s invo lved in the generat ion of chor oidal neovascular i zat ion.
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[Journal Article] Involvement of hyaluronan and its receptor CD44 with choroidal neovascularization2009
Author(s)
Mochimaru H, Takahashi E, Tsukamoto N, Miyazaki J, Yaguchi T, Koto T, Kurihara T, Noda K, Ozawa Y, Ishimoto T, Kawakami Y, Tanihara H, Saya H, Ishida S, Tsubota K.
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Journal Title
Invest Ophthalmol Vis Sci 50(9)
Pages: 4410-5
Peer Reviewed
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