2010 Fiscal Year Final Research Report
What has happened in the preliminary AV shunt loop?-Experiments in rabbits.
| Project/Area Number |
20791309
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Plastic surgery
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| Research Institution | Kagawa University |
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Principal Investigator |
KOGURE Tetsukuni Kagawa University, 医学部附属病院, 助教 (40437695)
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| Project Period (FY) |
2008 – 2010
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| Keywords | AV shunt loop / 乱流 / 血栓 |
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| Research Abstract |
The preliminary AV shunt loop is known as the simplified method of vein graft, and has been widely performed in the microsurgical reconstruction. However, this method involves the risk of thrombosis due to turbulence. In the present study, an experimental model of the preliminary AV shunt model was created to investigate what has happened in the AV shunt loop. The result showed that turbulent flow is likely to occur in the AV shunt loop and the shear stress over 200 dyne/cm^2 act on the outer side of the loop vessel. Conclusion : Endothelium damage under a high shear stress and turbulent flow were thought to cause a high incidence of thrombosis and obstruction in the most distal part of AV shunt loop.
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