2009 Fiscal Year Final Research Report
The effect of amylase-binding protein on formation of secretory granules in rat parotid gland.
Project/Area Number |
20791363
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Single-year Grants |
Research Field |
Functional basic dentistry
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Research Institution | Nihon University |
Principal Investigator |
KATO Osamu (勝俣 治) Nihon University, 松戸歯学部, 講師 (70349968)
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Project Period (FY) |
2008 – 2009
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Keywords | 歯学 / 生理学 / シグナル伝達 / 唾液腺 / 分泌顆粒 |
Research Abstract |
I hypothesized that rat parotid cell can take amylase from lumen to make secretory granule. I examined that whether parotid gland take color dye into granules by endocytosis, and that whether the dye can be detected in living cells. In this study, I succeeded in detection of fluorescence in immature granules. This result expects visualization of secretory granules. Next, I will examine granule maturation and exocytosis using that method.
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Research Products
(3 results)