2009 Fiscal Year Final Research Report
CAN THE SUPPRESSION OF BONE RESORPTION AT EXTRACTION SOCKET STIMULATE OSSEOINTEGRATION?
| Project/Area Number |
20791431
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Prosthetic dentistry
|
|---|
| Research Institution | Kyushu University |
|---|
Principal Investigator |
OGINO Yoichiro Kyushu University, 大学病院, 助教 (50380431)
|
|---|
| Project Period (FY) |
2008 – 2009
|
| Keywords | 再生医学 / 細胞・組織 / 歯学 / 動物 |
|---|
| Research Abstract |
The purpose of the present study was to evaluate the relationship between the suppression of bone resorption around the implant bone and osseointegration. As a bone resorption inhibitory factor, Interleukin- 1 receptor antibody (IL-1RA) inhibited the formation of osteoclast like cells in a dose-dependent manner in vitro. In the animal study, IL-1RA stimulated the peri-implant bone formation and cortical bone thickness.
|
