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2009 Fiscal Year Final Research Report

Development of odontogenic regenerative therapy by epithelial-mesenchymal interactions using ameloblast and odontoblast-lineage cell lines.

Research Project

  • PDF
Project/Area Number 20791490
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Surgical dentistry
Research InstitutionAkita University

Principal Investigator

NAKATA Akira  Akita University, 医学部, 助教 (50400510)

Project Period (FY) 2008 – 2009
Keywords歯の再生医療
Research Abstract

We try to develop the original tooth regenerative therapy by epithelial-mesenchymal interactions in vitro and in vivo using ameloblast, odontoblast-lineage cell line and scaffold which specialized in the tooth regenerative therapy.
In this study, after sub-cutaneous implantation of ameloblast-lineage cell line that cultured three-dimensional in matrigel to athymic nude mice, we ectopically observed enamel epithelium like structure formation and hard tissue construction. We believed that these cell lines are useful tool for clinical tissue engineering technology to repair the tooth

  • Research Products

    (5 results)

All 2009 2008

All Journal Article (1 results) Presentation (4 results)

  • [Journal Article] 口腔カンジダ症に対するイトラコナゾール内用液の治療効果について2009

    • Author(s)
      石田貴洋, 高野裕史, 中田憲, 伊藤悠, 本間高志, 鈴木正晴, 山下貴史, 大渕真彦, 五十嵐秀光, 海老原龍人, 今野泰典, 佐藤裕子, 福田雅幸
    • Journal Title

      J Michinoku Dent Soc 40(1・2)

      Pages: 47-48

  • [Presentation] 下顎骨に発生したエナメル上皮癌の2例2009

    • Author(s)
      中田憲, 伊藤悠, 高野裕史, 福田雅幸
    • Organizer
      第54回(社)日本口腔外科学会総会
    • Place of Presentation
      札幌
    • Year and Date
      20091000
  • [Presentation] 外側咽頭後リンパ節転移を生じた硬口蓋癌と上歯肉癌の2例2009

    • Author(s)
      中田憲, 伊藤悠, 高野裕史, 福田雅幸
    • Organizer
      第33回日本頭頸部癌学会
    • Place of Presentation
      札幌
    • Year and Date
      20090600
  • [Presentation] 歯由来細胞株を用いた歯の再生医療の開発:マウス皮下におけるエナメル芽細胞の石灰化2008

    • Author(s)
      中田憲, 永井宏和, 伊藤悠, 高野裕史, 福田雅幸, 宮本洋二
    • Organizer
      第53回(社)日本口腔外科学会総会
    • Place of Presentation
      徳島
    • Year and Date
      20081000
  • [Presentation] 口腔扁平上皮癌に対するS-1とTXT併用療法に関する臨床的検討2008

    • Author(s)
      中田憲, 永井宏和, 遊佐和之, 佐藤扶美子, 伊藤悠, 高野裕史, 福田雅幸, 宮本洋二
    • Organizer
      第32回日本頭頸部癌学会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-13

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Published: 2011-06-18   Modified: 2016-04-21  

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