2010 Fiscal Year Final Research Report
Elucidation of the role of serotonin and serotonin receptors in neuropathic pain in inferior alveolar nerve.
| Project/Area Number |
20791502
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
TSURUMAKI Tatsuru Niigata University, 医歯学系, 助教 (10345522)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 神経因性疼痛 / セロトニン |
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| Research Abstract |
I created an experimental animal model of neuropathic pain on the inferior alveolar nerve by using a modified method of the neuropathy model created by Yonehara et al. 5-HT1B, 1F, 2A mRNAs were detected by RT-PCR in rat inferior alveolar nerve. However, expressions of serotonin receptors mRNAs were not shown significant change.
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