2011 Fiscal Year Final Research Report
Elucidation of the salivary gland differentiation system which aimed at the salivary gland regenerative medicine
| Project/Area Number |
20791533
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2008 – 2011
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| Keywords | 唾液腺 / 再生医療 |
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| Research Abstract |
We established a model three-imensional reconstruction of tissue culture cell separation from the submandibular gland primordia in this study. Rebuild their organization, were also admitted the expression of aquaporin as a marker or terminal. differentiation. This phenomenon, in the salivary gland tissue has shown that it contains a group of cells s should be called stem cells. Brachury is a transcription factor T-box is a gene required in mesoderm rormation, expression Brachury in the normal salivary glands, recognized the increased expression of a sudden on embryonic day 13. 5, after embryonic day 14. 5 the amount of its expression decreased proved that.
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