2009 Fiscal Year Final Research Report
Analysis of regulatory mechanisms of odontoblast differentiationby novel gap junction protein
Project/Area Number |
20791583
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Single-year Grants |
Research Field |
Orthodontic/Pediatric dentistry
|
Research Institution | Kyushu University |
Principal Investigator |
IWAMOTO Tsutomu Kyushu University, 病院, 助教 (90346916)
|
Project Period (FY) |
2008 – 2009
|
Keywords | 歯胚発生 / 象牙芽細胞 / マトリックス蛋白 / 細胞間蛋白 |
Research Abstract |
To find genes, important for tooth development, we had generated tooth cDNA library, and have been trying to find novel and functional genes. So far, we have identified a novel matrix protein gene, named TM14/Fibluin7. We found that TM14/Fibluin 7 has an important role for odontoblast attachment. And also, we have identified a hard tissue specific novel gap junction gene, and have been analyzing its function in tooth, cartilage and bone development.
|
Research Products
(9 results)
-
[Journal Article] The critical role of heparin binding domains of ameloblastin for dental epithelium cell adhesion and ameloblastoma proliferation.2009
Author(s)
Sonoda A*, Iwamoto T*, Nakamura T, Fukumoto E, Yoshizaki K, Yamada A, Arakaki M, Harada H, Nonaka K, Nakamura S, Yamada Y, Fukumoto S.
-
Journal Title
J Biol Chem 284(40)
Pages: 27176-84
Peer Reviewed
-
-
-
-
-
-
-
-