2009 Fiscal Year Final Research Report
Mechanism of periodontal tissue destruction caused by Th17 axis.
| Project/Area Number |
20791608
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Tokyo Medical and Dental University |
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Principal Investigator |
KOBAYASHI Hiroaki Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 助教 (50396967)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 歯周免疫機能学 |
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| Research Abstract |
Periodontitis is an inflammatory disease caused by periodontopathic bacteria. The aim of this study was to clarify whether IL-23 production is correlated with periodontal tissue destruction. But, there was no correlation between IL-23 production from periodontitis patients monocytes and clinical parameters. As the severity of periodontitis was not correlated with IL-23 production, individual diversity in IL-23 might not affect the susceptibility of periodontitis directly.
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