2010 Fiscal Year Final Research Report
The balance of MMPs/TIMPs in gingival tissues of gingival overgrowth
| Project/Area Number |
20791609
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Niigata University |
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Principal Investigator |
NAKASONE Naohiro Niigata University, 医歯学総合病院, 医員 (20447634)
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| Project Period (FY) |
2008 – 2010
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| Keywords | 歯肉増殖症 / tissue inhibitors of metalloproteinases (TIMPs) / metalloproteinases (MMPs) / 歯周炎 / calcium-channel blocker |
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| Research Abstract |
We analyzed gene expression and protein localization of metalloproteinases (MMP)-1 and tissue inhibitors of metalloproteinases (TIMP)-1, -2, -3, and -4 in gingival tissues of gingival overgrowth and periodontitis. In particular, our data in TIMP-3 and -4 mRNA expression and protein localization accepted and published in Archives of Oral Biology.
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