• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2009 Fiscal Year Final Research Report

Molecular biological analysis of periodontitis and metabolic syndrome based on renin-angiotenshin system

Research Project

  • PDF
Project/Area Number 20791618
Research Category

Grant-in-Aid for Young Scientists (B)

Allocation TypeSingle-year Grants
Research Field Periodontal dentistry
Research InstitutionKagoshima University

Principal Investigator

NAKAMURA Toshiaki  Kagoshima University, 大学院・医歯学総合研究科, 助教 (60381183)

Project Period (FY) 2008 – 2009
Keywords歯周病 / 歯肉 / メタボリックシンドローム / アンジオテンシン / RAS
Research Abstract

The aim of the present study was to investigate the expression of renin-angiotensin system (RAS) components, which has been considered to be concerned with several steps of metabolic syndrome, in human gingival tissues and the effects of RAS on inflammatory reactions in cultured human gingival fibroblasts (HGF). This study demonstrated that tissue RAS exists in HGT and IL-6 induced by IL-1β may be partially regulated through AT1R in HGF. These facts suggest that RAS may be involved in the regulation of inflammatory responses in periodontal disease.

URL: 

Published: 2011-06-18   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi