2009 Fiscal Year Final Research Report
The role of anti-phosholipid antibody against periodontal pathogen to facilitate cardiovascular disease.
| Project/Area Number |
20791627
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Periodontal dentistry
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| Research Institution | Aichi Gakuin University |
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Principal Investigator |
HISHIKAWA Toshimitsu Aichi Gakuin University, 歯学部, 非常勤講師 (10421249)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 歯周免疫機能学 |
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| Research Abstract |
oxLDL opsonized with anti-phospholipid promotes production of proinflammatory cytokines by DCs and NK cells and thus may participate in the pathogenesis of atherosclerosis. Opsonization of oxLDL by anti-phospholipid could provide a mechanism to help explain why periodontitis patients are more likely to develop atherosclerosis.
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