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2010 Fiscal Year Final Research Report

Investigation of the molecular functions of Septin family molecules

Research Project

  • PDF
Project/Area Number 20800086
Research Category

Grant-in-Aid for Young Scientists (Start-up)

Allocation TypeSingle-year Grants
Research Field Neuroscience in general
Research InstitutionInstitute for Developmental Research, Aichi Human Service Center

Principal Investigator

SHINODA Tomoyasu  Institute for Developmental Research, Aichi Human Service Center, 研究員 (80505652)

Project Period (FY) 2008 – 2010
Keywords大脳皮質 / 神経発生 / 細胞遊走
Research Abstract

Septin family molecules are highly conserved in eukaryotic cells. Although everal septins are specifically expressed in neuronal tissues, little is known about their physiological functions. Our research revealed that Sept14 is involved in cortical neuronal migration during corticogenesis, via interaction with Sept4.

  • Research Products

    (18 results)

All 2010 2009 2008 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (12 results) Book (2 results) Remarks (1 results)

  • [Journal Article] Septin 14 is involved in cortical neuronal migration via interaction with Septin 4.2010

    • Author(s)
      Shinoda T, Ito H, Sudo K, Iwamoto I, Morishita R, Nagata K.
    • Journal Title

      Molecular Biology of the Cell 21

      Pages: 1324-1334

    • Peer Reviewed
  • [Journal Article] Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation.2010

    • Author(s)
      Ito H, Morishita R, Shinoda T, Iwamono I, Okamoto K, Nagata K.
    • Journal Title

      Molecular Psychiatry 15

      Pages: 976-986

    • Peer Reviewed
  • [Journal Article] Proteomic analysis reveals novel binding partners of dysbindin, a schizophrenia-related protein.2009

    • Author(s)
      Hikita T, Taya S, Fujino Y, Taneichi-Kuroda S, Ohta K, Tsuboi D, Shinoda T, Kuroda K, Funahashi Y, Uraguchi-Asaki J, Hashimoto R, Kaibuchi K.
    • Journal Title

      Journal of Neurochemistry 110

      Pages: 1567-1574

    • Peer Reviewed
  • [Presentation] 大脳皮質形成におけるSeptinファミリー分子の機能2010

    • Author(s)
      篠田友靖
    • Organizer
      愛知県心身障害者コロニー発達障害研究所公開シンポジウム
    • Place of Presentation
      愛知
    • Year and Date
      2010-12-22
  • [Presentation] Molecular mechanism of septin-mediated neuronal migration2010

    • Author(s)
      篠田友靖, ほか
    • Organizer
      BMB2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
  • [Presentation] Sept14 is involved in neuronal migration via interaction with Sept42010

    • Author(s)
      篠田友靖, et. al.
    • Organizer
      Neuroscience2010
    • Place of Presentation
      San Diego
    • Year and Date
      2010-11-13
  • [Presentation] Septinの大脳皮質形成における機能および分子メカニズム2010

    • Author(s)
      篠田友靖, ほか
    • Organizer
      Neuro2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-08
  • [Presentation] Septin 14 is involved in cortical neuronal migration via interaction with Septin 42010

    • Author(s)
      篠田友靖, ほか
    • Organizer
      第74回生化学会中部支部例会・シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-23
  • [Presentation] Roles of Septins in Neuronal Migration2009

    • Author(s)
      篠田友靖, ほか
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
  • [Presentation] Novel function of Septin in neuronal migration2009

    • Author(s)
      篠田友靖, ほか
    • Organizer
      名古屋大学グローバルCOEプログラム第2回国際シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2009-11-18
  • [Presentation] Sept14の大脳皮質形成における機能2009

    • Author(s)
      篠田友靖, ほか
    • Organizer
      Neuro2009
    • Place of Presentation
      名古屋
    • Year and Date
      2009-09-06
  • [Presentation] Sept14 is involved in proper positioning of cortical pyramidal neuron2009

    • Author(s)
      篠田友靖, ほか
    • Organizer
      名古屋大学グローバルCOEプログラム第1回国際シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2009-01-22
  • [Presentation] Possible function of a multiadaptor protein, p140Cap, in exocytosis2008

    • Author(s)
      篠田友靖, ほか
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
  • [Presentation] Sept14の皮質神経細胞局在化における機能2008

    • Author(s)
      篠田友靖, ほか
    • Organizer
      第51回日本神経化学会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-08
  • [Presentation] 統合失調症発症脆弱性因子DISC1の機能解析2008

    • Author(s)
      篠田友靖, ほか
    • Organizer
      第72回日本生化学会中部支部例会・シンポジウム
    • Place of Presentation
      岐阜
    • Year and Date
      2008-05-20
  • [Book] SNARE複合体形成におけるセプチンの役割(61)2010

    • Author(s)
      伊東秀記、篠田友靖、永田浩一
    • Total Pages
      242-246
    • Publisher
      生体の科学
  • [Book] 統合失調症脆弱性遺伝子DISC1の生理機能(34)2008

    • Author(s)
      篠田友靖
    • Total Pages
      5-6
    • Publisher
      Medical Science Digest
  • [Remarks] ホームページ等

    • URL

      http://www.inst-hsc.jp

URL: 

Published: 2012-01-26   Modified: 2016-04-21  

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