2009 Fiscal Year Final Research Report
Development of artificial peripheral nerve for regenerative medicine
| Project/Area Number |
20860063
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| Research Category |
Grant-in-Aid for Young Scientists (Start-up)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kyushu University |
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Principal Investigator |
TAKEI Takayuki Kyushu University, 大学院・工学研究院, 助教 (90468059)
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| Project Period (FY) |
2008 – 2009
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| Keywords | 末梢神経 / 生体組織工学 / ヒドロゲル / 中空ファイバー |
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| Research Abstract |
Calcium-alginate hollow microfibers with various outer (100-800μm) and inner diameters (inner diameter/outer diameter=0.06-0.80) were successfully fabricated using a spinning system consisted of a triple extrusion head. Stretching the microfibers resulted in decrease in outer diameter of them (less than 100μm). Immobilization of gelatin into the microfibers enhanced adhesion and proliferation of enclosed mammalian cells, such as neuronal cell and glial cell lines.
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